{"id":1250,"date":"2024-10-04T14:05:07","date_gmt":"2024-10-04T12:05:07","guid":{"rendered":"https:\/\/www.extrapopusti.rs\/Blog\/?p=1250"},"modified":"2024-10-04T15:35:22","modified_gmt":"2024-10-04T13:35:22","slug":"menopauza-i-osteoporoza","status":"publish","type":"post","link":"https:\/\/www.extrapopusti.rs\/Blog\/menopauza-i-osteoporoza\/","title":{"rendered":"Menopauza i osteoporoza"},"content":{"rendered":"
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\"\"Osteoporoza \u2013 genetika ili posledica menopauze<\/strong><\/h5>\n
<\/h5>\n<\/div>\n<\/div>\n
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Od kada se rodimo prolazimo kroz raznorazne promene, kako fizi\u010dke tako i psihi\u010dke. Neke podnesemo lak\u0161e, dok nam neke predstavljaju problem. Va\u017eno je da razumemo na\u0161 organizam i \u0161ta \u017eeli da nam poru\u010di. Kod \u017eena, menopauze je svakako jedno od te\u017eih perioda tokom \u017eivota, jer su promene dosta velike i nagle. Ona sa sobom donosi i neke nove simptome, ali i bolesti. Ipak, re\u0161enje za ubla\u017eavanje simptoma kao i bolesti postoji. Klju\u010d svega le\u017ei u dobroj informisanosti i redovnoj poseti va\u0161em izabranom lekaru. Zbog toga smo za vas pripremili tekst o \u201etihoj\u201c bolesti koja se naj\u010de\u0161\u0107e javlja upravo u menopauzi.<\/p>\n<\/div>\n<\/div>\n

\u0160ta menopauza predstavlja?<\/strong><\/h5>\n

Menopauza ozna\u010dava poslednju menstruaciju, odnosno prestanak menstrualnog krvarenja i zavr\u0161etak reproduktivnog ciklusa \u017eene. Obi\u010dno nastaje izme\u0111u 45. i 55. godine \u017eivota, a u na\u0161oj populaciji, u proseku, u 49,5 godina. Navedeni period ulaska u menopauzu odnosi se na spontani (prirodni) ulazak u menopauzu, ali postoji i indukovani ili arteficijalni ulazak u menopauzu, koji nastaje kao posledica operativnog uklanjanja genitalnih organa \u017eene, jajnika i materice.<\/p>\n

Uzrok prirodnog ulaska u menopauzu je smanjenje funkcije jajnika koje za posledicu ima, najpre, smanjenje, a zatim i potpuni prestanak stvaranja \u017eenskih polnih hormona, estrogena i progesterona, ali i mu\u0161kih polnih hormona (testosterona i dehidroepiandrosterona) koji tako\u0111e imaju zna\u010dajnu ulogu u funkcionisanju \u017eenskih polnih organa.<\/h5>\n
Menopauza: Simptomi i znakovi<\/strong><\/h5>\n

Simptomi i znakovi menopauze, zapravo, izraz su telesnog prilago\u0111avanja na manjak ili odsustvo estrogena. Pra\u0107eni su promenama u gra\u0111i i funkciji organa i organskih sistema, pre svega promenama u lu\u010denju hormona i funkcionisanju enzimskih sistema bitnih za odvijanje metaboli\u010dkih procesa u organizmu. Prve promene u hormonskom statusu \u017eene u menopauzi, koje podrazumevaju sni\u017eene nivoe estrogena, ali i progesterona, dovode do ispoljavanja simptoma menopauze koje se manifestuju na razli\u010ditim nivoima:<\/p>\n

Promene na nivou CNS-a nastaju kao posledica smanjenog nivoa serotonina i ispoljavaju se napeto\u0161\u0107u, promenom raspolo\u017eenja, smanjenjem koncentracije, nesanicom ili poreme\u0107ajem ritma spavanja.<\/p>\n

\"\"Promene na hormonski zavisnim tkivima urogenitalnog sistema nastaju kao posledica smanjenja estrogena (hipoestrogenemija) koje dovodi do atrofije (istanjivanja) vaginalnih zidova, ali i promena na spoljnim genitalnim organima, suvo\u0107e, smanjene elasti\u010dnosti sluzoko\u017ee, sklonosti ka infekcijama.<\/p>\n

Vazomotorni poreme\u0107aji koji se javljaju u vidu valunga i no\u0107nog znojenja.<\/p>\n

Promene na kardiovaskularnom sistemu (naj\u010de\u0161\u0107a posledica je pojava povi\u0161enog krvnog pritiska i ateroskleroze).<\/p>\n

Promene na ko\u0161tano-zglobnom sistemu (osteoporoza).<\/p>\n

Na\u017ealost, promenama na ko\u0161tano-zglobnom sistemu, uz sve gore navedene simptome, \u017eene u menopauzi pridaju najmanje zna\u010daja. Promene mogu biti i asimptomatske, ali i ako se jave stavljaju se u zape\u0107ak ili se pripisuju simptomima vezanim za druge organe.<\/p>\n

\u0160ta je osteoporoza?<\/strong><\/h5>\n

Osteoporoza je bolest ko\u0161tanog tkiva koju karakteri\u0161e gubitak ko\u0161tane mase (organskog i mineralnog dela kosti) i pove\u0107ana razgradnja kostiju, \u0161to dovodi do promene mikroarhitekture (gra\u0111e) ko\u0161tanog tkiva i rezultira ve\u0107om krtostju i lomljivo\u0161\u0107u kostiju. Proces stvaranja i razgradnje kosti je normalan (fiziolo\u0161ki) i kontinuirano se odvija tokom celog \u017eivota. U normalnim uslovima, ova dva procesa su uravnote\u017eena.<\/p>\n

Me\u0111utim, nastupanjem menopauze dolazi do pove\u0107ane aktivnosti \u0107elija koje razgra\u0111uju ko\u0161tano tkivo (osteoklasti), dok se funkcija \u0107elija koje stvaraju kost (osteoblasti) smanjuje, \u0161to dovodi do smanjenja koli\u010dine i kvaliteta ko\u0161tane mase. Osobe sa manjom telesnom masom, smanjenom fizi\u010dkom aktivno\u0161\u0107u, nedostatkom vitamina D i smanjenim unosom kalcijuma imaju ve\u0107i rizik za razvoj osteoporoze. Kod \u017eena u menopauzi dolazi i do promena u metabolizmu kalcijuma, koje mogu dovesti do znatno pove\u0107anog nivoa kalcijuma u odnosu na predmenopauzalni period, sa akumulacijom kalcijuma u krvnim sudovima i drugim organima.<\/p>\n

Menopauza i osteoporoza: Prevencija i suplementacija<\/strong><\/h5>\n

Prevencija podrazumeva adekvatno i blagovremeno reagovanje na prve simptome manjka estrogena, ne samo za re\u0161avanje uobi\u010dajenih simptoma menopauze (valunga, atrofije genitalnih organa), ve\u0107 i za prevenciju i tretman promena na ko\u0161tano-zglobnom sistemu povezanih sa menopauzom. Pored razmatranja hormonske supstitucione terapije ili suplementacije preparatima na bazi fitoestrogena, potrebno je korigovati \u017eivotni stil, uklju\u010duju\u0107i ishranu i fizi\u010dku aktivnost. Va\u017ena je i suplementacija, odnosno uzimanje preparata za adekvatnu mineralizaciju kostiju i spre\u010davanje nastanka i napredovanja osteoporoze. Ne treba zanemariti ni promene u metabolizmu kalcijuma, te je potrebna odgovaraju\u0107a supstitucija koja \u0107e korigovati nastale promene.<\/p>\n

Vitamin K2<\/strong>\u00a0je neophodan za aktivaciju proteina osteokalcina, klju\u010dnog za vezivanje kalcijuma i njegovu iskoristljivost. Vitamin K2 omogu\u0107ava uklanjanje kalcijuma iz krvnih sudova i drugih organa i poma\u017ee ugradnji kalcijuma tamo gde je potrebno, u kost. Klju\u010dna je i suplementacija vitaminom D, jer smanjena koncentracija vitamina D dovodi do nedovoljne resorpcije kalcijuma u crevima, ubrzavaju\u0107i razgradnju kosti.<\/p>\n","protected":false},"excerpt":{"rendered":"

Osteoporoza \u2013 genetika ili posledica menopauze Od kada se rodimo prolazimo kroz raznorazne promene, kako fizi\u010dke tako i psihi\u010dke. Neke podnesemo lak\u0161e, dok nam neke predstavljaju problem. Va\u017eno je da razumemo na\u0161 organizam i \u0161ta \u017eeli da nam poru\u010di. Kod…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[1573,1572,666,1574],"class_list":["post-1250","post","type-post","status-publish","format-standard","hentry","category-extrapopusti","tag-menopauza-simptomi-i-znakovi","tag-osteoporoza-genetika-ili-posledica-menopauze","tag-prevencija","tag-suplementacija"],"yoast_head":"\nMenopauza i osteoporoza | Popusti<\/title>\n<meta name=\"description\" content=\"Menopauza i osteoporoza: Prevencija i suplementacija. 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